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On the Role of Ligand in Retinoid Signaling: Positive Cooperativity in the Interactions of 9-cis Retinoic Acid with Tetramers of the Retinoid X Receptor

✍ Scribed by Kersten, Sander; Pan, Lily; Noy, Noa


Book ID
125974520
Publisher
American Chemical Society
Year
1995
Tongue
English
Weight
831 KB
Volume
34
Category
Article
ISSN
0006-2960

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We have investigated the expression of the retinoid X receptor-␣ (RXR␣) gene in the developing chicken embryo by using nonradioactive wholemount in situ hybridization. At the earliest stage of development examined (stage 9; J. Morphol. 88:49-92), we detect RXR␣ transcripts in a stretch of neuroepith