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9-Borabicyclo[3.3.2]decanes and the Asymmetric Hydroboration of 1,1-Disubstituted Alkenes

✍ Scribed by Gonzalez, Ana Z.; Román, José G.; Gonzalez, Eduvigis; Martinez, Judith; Medina, Jesus R.; Matos, Karl; Soderquist, John A.


Book ID
127069661
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
258 KB
Volume
130
Category
Article
ISSN
0002-7863

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Asymmetric Hydroboration of 1,1-Disubsti
✍ Stephen P. Thomas; Varinder K. Aggarwal 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 262 KB 👁 2 views

## Abstract **A breakthrough** in the asymmetric hydroboration of notoriously difficult 1,1‐disubstituted alkenes using a new family of highly effective hydroboration reagents is described (see scheme). The intermediate boranes can be oxidized to alcohols or used in Suzuki–Miyaura cross‐coupling re