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89 The effect of apoptosis in cerebellar granule cells on tau

โœ Scribed by N. Canut; M. Novak; L. Dusl; T. Ciotil; P. Calissano; A. Bradbury

Book ID
117413822
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
149 KB
Volume
17
Category
Article
ISSN
0197-4580

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Caspase-3 activity increased dramatically in cytosolic extracts of rat cerebellar granule cells exposed to apoptotic conditions (basal medium Eagle (BME) containing 5 mM K ุ‰ without serum) when assayed with Ac-DEVD-amc, but not with Ac-YVAD-afc, a preferred substrate for caspase-1. This provided a b