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8749 POSTER Carboplatin Chemotherapy in Patients With Recurrent High-grade Glioma

✍ Scribed by Kaloshi, G.; Rroji, A.; Bushati, T.; Petrela, M.


Book ID
123133711
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
39 KB
Volume
47
Category
Article
ISSN
0959-8049

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## Abstract ## BACKGROUND Doxorubicin exhibits high efficacy in malignant glioma cell cultures. Nonetheless, as a standard formulation, doxorubicin has not been used clinically, due to poor penetration of the blood‐brain barrier. Furthermore, doxorubicin is known to induce tumor resistance genes.