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844 Blocking expression of the tumour suppressor gene, p63 inhibits in-vivo carcinogenesis in prostate cancer

โœ Scribed by Beekharry, R.; Bansema, W.; Berry, P.; Walker, H.; Nicholl, A.; Simms, M.; Collins, A.; Maitland, N.


Book ID
122433769
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
108 KB
Volume
13
Category
Article
ISSN
1569-9056

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The KAI1 gene, isolated from human chromosome 11p11.2, has been implicated as a prostate cancer metastasis suppressor gene. Recent studies have demonstrated that the expression of KAI1 protein is reduced in metastases of human prostate cancers and is inversely correlated with tumour grade. The objec