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Prognostic significance of downregulated expression of the candidate tumour suppressor gene SASH1 in colon cancer

✍ Scribed by Rimkus, C; Martini, M; Friederichs, J; Rosenberg, R; Doll, D; Siewert, J R; Holzmann, B; Janssen, K P


Book ID
121712712
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
136 KB
Volume
95
Category
Article
ISSN
0007-0920

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## Abstract Aneuploidy and genetic instability are a hallmark of colorectal cancer and other solid tumors, and they are thought to enhance tumor progression. The gene __MAD2L____2__ (mitotic arrest deficient 2‐like 2) encodes the spindle checkpoint protein MAD2L2 (or MAD2B), a key component of a su