8402 human cell culture — A model for evaluating bilirubin-albumin interactions with drug
✍ Scribed by Arun K. Pramanik; Nancy Horn; Gregory Schwemer
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- English
- Weight
- 198 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0300-483X
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Abbreviations: HSC, hepatic stellate cells; M6P/IGF-II receptor, mannose 6-phosphate/ insulin-like growth factor II receptor; M6P, mannose 6-phosphate; M6P x -HSA, human serum albumin with x molecules of mannose 6-phosphate per molecule of human serum albumin; L-TGF, latent transforming growth fact
This study tests the hypothesis that human nasal RPMI 2650 cells grown at an air-liquid interface is a feasible model for drug transport studies via the nasal route. RPMI 2650 cells were cultured in Eagle's minimal essential medium (MEM) at both air-liquid and liquid-liquid interfaces. For each cult