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83 Antitumor activities of MGCD0103, a novel isotype-selective histone deacetylase inhibitor

✍ Scribed by Z. Li; N. Zhou; M. Fournel; G. Rahil; J. Wang; D. Delorme; O. Moradei; R. MacLeod; J. Besterman


Book ID
118621267
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
147 KB
Volume
2
Category
Article
ISSN
1359-6349

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## Abstract Histone deacetylase (HDAC) inhibitors are among the most promising targeted anticancer agents and are potent inducers of growth arrest, differentiation, and/or apoptotic cell death of transformed cells. In this study, antitumor effects of a novel sulfur‐containing hydroxamate HDAC inhib