## Abstract For Abstract see ChemInform Abstract in Full Text.
8-Aryl xanthines potent inhibitors of phosphodiesterase 5
โ Scribed by Ruth Arnold; David Beer; Gurdip Bhalay; Urs Baettig; Stephen P Collingwood; Sarah Craig; Nicholas Devereux; Andrew Dunstan; Angela Glen; Sylvie Gomez; Sandra Haberthuer; Trevor Howe; Stephen Jelfs; Heinz Moser; Reto Naef; Paul Nicklin; David Sandham; Rowan Stringer; Katharine Turner; Simon Watson; Mauro Zurini
- Book ID
- 108477278
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 194 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0960-894X
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๐ SIMILAR VOLUMES
Several derivatives of two mesoionic xanthine analogs, mesoionic thiazolo[3,2-alpha]pyrimidine-5,7-diones and mesoionic 1,3,4-thiadiazolo[3,2-alpha]pyrimidine-5,7-diones, were synthesized and evaluated as inhibitors of cyclic AMP phosphodiesterase. A significant number of these compounds demonstrate