Identification of cytogenetic subgroups
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Mattias HΓΆglund; Laurie Sehn; Joseph M. Connors; Randy D. Gascoyne; Reiner Siebe
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Article
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2003
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John Wiley and Sons
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English
β 215 KB
## Abstract Follicular lymphoma (FL) is characterized by the activation of __BCL2__ through t(14;18)(q32;q21). Additional acquired mutations are necessary to generate a fully malignant clonal proliferation. Many of these secondary genetic alterations are visible in the clonal karyotype; however, th