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76 Inhibition of primary tumor growth in mice by urokinase receptor antagonists

Book ID: 114201200
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 128 KB
Volume: 10
Category: Article
ISSN: 0268-9499
DOI: 10.1016/s0268-9499(96)80164-0

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## Abstract Malignant cells possess a high degree of proteolytic activity in which the plasminogen activator system plays an important role. An increased expression of urokinase type plasminogen activator (uPA) is of significance for degradation of the extracellular tumor matrix, facilitating invas