𝔖 Bobbio Scriptorium
✦   LIBER   ✦

752 The apolipoprotein E e4 allele in Parkinson disease with and without Alzheimer lesions

✍ Scribed by R. Egensperger; C. Bancher; S. Kösel; K. Jellinger; P. Mehraein; M.B. Graeber


Book ID
117414153
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
142 KB
Volume
17
Category
Article
ISSN
0197-4580

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Alzheimer's disease and apolipoprotein e
✍ M. A. Pericak-Vance; C. C. Johnson; J. B. Rimmler; A. M. Saunders; L. C. Robinso 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 519 KB

## Abstract Alzheimer's Disease (AD) is a complex genetic disorder with four loci already identified. Mutations in three of these, the amyloid precursor protein, presenilin I, and preseuilin II, cause early‐onset AD. The apolipoprotein E (APOE) gene contributes primarily to late‐onset AD. The APOE‐

Apolipoprotein E-η4 allele and familial
✍ Ge Li; Jeremy M. Silverman; Larry D. Altstiel; Vahram Haroutunian; Daniel P. Per 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 910 KB

Recent studies have 'found an association between presence of apolipoprotein E (APOE) €4 allele and Alzheimer's disease (AD). The present study compared the cumulative risk of primary progressive dementia (PPD) in relatives of AD probands carrying at least one copy of the €4 allele with the relative