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73. Triptolide Therapy for Neuroblastoma Decreases Cell Viability in Vitro and Inhibits Tumor Growth in Vivo

✍ Scribed by M.B. Antonoff; D. Borja-Cacho; R. Chugh; B. Sorenson; D.A. Saltzman; A.K. Saluja; S.M. Vickers


Book ID
116704645
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
421 KB
Volume
151
Category
Article
ISSN
0022-4804

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## Abstract We have recently described MAZ51, an indolinone that blocks the ligand‐induced autophosphorylation of VEGFR‐3, a receptor tyrosine kinase that plays a central role in the regulation of lymphangiogenesis. Here we show that MAZ51 is able to block the proliferation of VEGFR‐3‐expressing hu