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718CYP17 polymorphisms and prostate cancer

✍ Scribed by Mearini L.; Mearini E.; Zucchi A.; Costantini E.; Porena M.

Book ID: 118646847
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 158 KB
Volume: 4
Category: Article
ISSN: 1569-9056
DOI: 10.1016/s1569-9056(05)80722-5

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## Abstract Because androgens likely play a key role in prostate growth and prostate cancer development, variants of genes involved in androgen biosynthesis may be related to prostate cancer risk. The enzyme P450c17α, encoded by the __CYP17__ gene, catalyzes the conversion of progesterone and pregn