7-Oxo-4,5,6,7-tetrahydro-1 H -pyrazolo[3,4- c ]pyridines as Novel Inhibitors of Human Eosinophil Phosphodiesterase
โ Scribed by Duplantier, Allen J.; Andresen, Catharine J.; Cheng, John B.; Cohan, Victoria L.; Decker, Christian; DiCapua, Frank M.; Kraus, Kenneth G.; Johnson, Kerry L.; Turner, Claudia R.; UmLand, John P.; Watson, John W.; Wester, Ronald T.; Williams, Alison S.; Williams, John A.
- Book ID
- 121373498
- Publisher
- American Chemical Society
- Year
- 1998
- Tongue
- English
- Weight
- 260 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0022-2623
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๐ SIMILAR VOLUMES
## Abstract A facile synthesis of __trans__ isomers of 4โarylโ3โmethylโ6โoxoโ4,5,6,7โtetrahydro**โ**2__H__**โ**pyrazolo[3,4โ__b__]pyridineโ5โcarbonitriles via threeโcomponent condensation reaction of an aldehyde, 3โaminoโ5โmethylpyrazole and ethyl cyanoacetate in acetonitrile has been developed und