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7-Hydroxy-methotrexate and clinical toxicity following high-dose methotrexate therapy

โœ Scribed by R. Erttmann; S. Bielack; G. Landbeck


Book ID
112645331
Publisher
Springer-Verlag
Year
1985
Tongue
English
Weight
231 KB
Volume
109
Category
Article
ISSN
1432-1335

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High dose methotrexate therapy of solid
โœ Isacoff, William H. ;Townsend, Courtney M. ;Eilber, Frederick R. ;Forster, Terry ๐Ÿ“‚ Article ๐Ÿ“… 1976 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 464 KB

## Abstract In clinical studies performed during 111 infusions of high dose methotrexate (MTX) we have evolved a clinical and laboratory protocol which permits such therapy without prohibitive risk to the patient. The plasma MTX data obtained indicate that pharmacokinetic disposition is dose relate