6π-electrocyclization of azahexa-1,3,5-trienes: a new entry to a regiospecific synthesis of 3-aryl(heteroaryl)pyridines
✍ Scribed by Pedro Molina; Aurelia Pastor; Maria Jesús Vilaplana
- Book ID
- 108371708
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- French
- Weight
- 628 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0040-4020
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Eingegangen am 16. Juli 1986 New 3-(pyridin-6-yl) pyraolo [ 1,5-u]pyrimidines were synthesized from (pyridin-6-y1)malonodinitrile 58, ethyl (pyridin-6-y1)cyanoacetate 5b and (pyridin-6-y1)benzoylacetonitrile 5c. Compounds 58-c were obtained from the 4,4,4-trichlorobut-2-enenitriles 2 and 1-pheny1et
## Abstract 1‐Substituted‐3‐dimethylaminopropenones **1a‐d** reacted with acetylacetone and with ethyl acetoacetate to yield regioselectively 2,3,6‐trisubstituted pyridines. Refluxing **1a‐d** in acetic acid/ammonium acetate resulted in the formation of 6‐substituted‐3‐aroylpyridines, whereas reflu