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A short and general synthesis of 1,3-dihydro-6-heteroaryl-5-perfluoroalkyl-2H-imidazo[4,5-b]pyridin-2-ones

โœ Scribed by Gee-Hong Kuo; Edward R. Bacon; Baldev Singh; Michael A. Eissenstat; George Y. Lesher


Book ID
112130541
Publisher
Journal of Heterocyclic Chemistry
Year
1993
Tongue
English
Weight
269 KB
Volume
30
Category
Article
ISSN
0022-152X

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Preparation of substituted 1,3-dihydro-2
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## Abstract A new synthetic route to 6โ€substitutedโ€imidazo[4,5โ€__c__]pyridinโ€2โ€ons from 4โ€aminopyridine has been investigated. 4โ€Aminopyridine protected as alkyl carbamates were nitrated with dinitrogen pentoxide to the corresponding methyl, __i__โ€propyl and __t__โ€butyl 3โ€nitropyridinโ€4โ€yl carbamat