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688 Highly Efficient Differentiation of Human Embryonic Stem Cells to Metabolically Active Hepatocytes In Vitro and In Vivo

โœ Scribed by Hay, David C.; Fletcher, Judy; Payne, Catherine; Terrace, John; Gallagher, Ronald; Black, James R.; Pryde, Anne; Filippi, Celine; Forbes, Stuart J.; Samuel, Kay; Ross, James A.; Iredale, John P.; Newsome, Philip

Book ID
122843045
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
65 KB
Volume
134
Category
Article
ISSN
0016-5085

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Orthotropic liver transplantation is the only established treatment for end-stage liver diseases. Utilization of hepatocyte transplantation and bio-artificial liver devices as alternative therapeutic approaches requires an unlimited source of hepatocytes. Stem cells, especially embryonic stem cells,