684 ApoE genotyping as a diagnostic test in suspected Alzheimer's disease
β Scribed by W.A. van Gool
- Book ID
- 118578160
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 126 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0197-4580
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π SIMILAR VOLUMES
## Abstract ## Objective The association between the APOE __Ξ΅__4 allele and depression was investigated in a retrospective study of 323 AD patients. ## Methods Patients were divided into demographically comparable groups based on the presence or absence of depression. ## Results Results showed
The apolipoprotein E (ApoE) genotype is a significant risk factor and modulator of age of onset of Alzheimer's disease (AD). We analyzed the effect of the ApoE genotype in two distinct early-onset familial AD groups: families with a mutation in the presenilin-1 gene (PS-1) on chromosome 14, and fami