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675 Overexpression of HOXB7 homeobox gene in oral cancer induces cellular proliferation and is associated with poor prognosis

✍ Scribed by C. Cavalcante Bitu; M.F.S.S. Destro; K.G. Zecchin; E. Graner; M.A. Lopes; L.P. Kowalski; R.D. Coletta


Book ID
119602452
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
47 KB
Volume
8
Category
Article
ISSN
1359-6349

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The pituitary tumor transforming gene 1 (PTTG1) protein is cell-cycle regulated and is identified as a human securin that inhibits sister chromatid separation and is involved in transformation and tumorigenesis. PTTG1 has very low or undetectable expression in most normal human tissues, but it is ab