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662 Urokinase plasminogen activator, a potential prognostic marker for node-negative breast cancer

✍ Scribed by M.J. Duffy; C. Duggan; H. Mulcahy; E.W. McDermott; J.J. Fenelly; J. Crown; N.J. O’Higgins


Book ID
116167408
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
148 KB
Volume
31
Category
Article
ISSN
0959-8049

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Urokinase plasminogen activator: A progn
✍ Duffy, Michael J.; Maguire, Teresa M.; McDermott, Enda W.; O'Higgins, Niall 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 143 KB 👁 2 views

Urokinase plasminogen activator (uPA) is a serine protease causally involved in cancer invasion and metastasis. Consistent with its role in cancer spread, uPA has been shown to be a prognostic marker in a variety of malignancies, especially breast cancer. Approximately 20 different groups have shown