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639 Usage of PCR-SSCP in the detection of P53 gene mutation in preserved sputum for the diagnosis of lung cancer

✍ Scribed by Logyun, G; Lejie, Cao; Zijian, Guo; Yuanjue, Zhu


Book ID
122408843
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
157 KB
Volume
18
Category
Article
ISSN
0169-5002

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Detection of p53 gene mutation by rapid
✍ Richie Soong; Barry J. Iacopetta; Jennet M. Harvey; Gregory F. Sterrett; Hugh J. πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 French βš– 73 KB πŸ‘ 2 views

We examined the association between mutation of the p53 gene and survival in a large cohort of breast cancer patients. Using a rapid, non-isotopic single-strand conformation polymorphism (SSCP) method we screened for mutations in exons 4-10 of the p53 gene in 375 primary breast cancers from patients