634 Cyfra 21-1: Clinical value in lung cancer (LC)
β Scribed by Rusu, P.; Ghilezan, N.; Bojan, O.; Ioan, A.; Cernea, D.; Ciuleanu, T.E.
- Book ID
- 122473771
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 301 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0169-5002
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Background. It is known that cytokeratin 19is particularly abundant in carcinoma of the lung. Methods. A sandwich enzyme-linked immunosorbent assay called CYFRA 21-1 was, therefore, developed to detect soluble cytokeratin 19 fragments in serum using two specific monoclonal antibodies (Ks 19.1 and B
## BACKGROUND. Cytokeratins are the intermediate filaments of the cytoskeletal protein located in normal epithelia, tumor, and cultured cells. Recently, a fragment of cytokeratin subunit 19, referred to as CYFRA 21-1, detected in the serum OF patients with nonsmall cell lung cancer, has been repor