Intravenous pharmacokinetics and absolut
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Dan C. Dimmitt; Youn Sung Choo; Lorene A. Martin; Thangam Arumugham; William F.
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Article
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1999
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John Wiley and Sons
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English
β 766 KB
In this first part of a two-part investigation, the intravenous dose proportionality of dolasetron mesylate, a 5-HT 3 receptor antagonist, and the absolute bioavailability of oral dolasetron mesylate were investigated. In an open-label, randomized, four-way crossover design, 24 healthy men between t