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6065 POSTER Significance of Mutation in K-Ras Gene in Pathogenesis and Clinical Course of Colorectal Cancer

✍ Scribed by Belyaeva, A.V.; Yanus, G.A.; Imyanitov, E.N.; Suspitsin, E.N.; Goulyaev, A.V.; levleva, A.G.; Moiseenko, A.B.

Book ID
122566185
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
54 KB
Volume
47
Category
Article
ISSN
0959-8049

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## Abstract Gene mutations in __APC__, __K‐ras__, and __p53__ are thought to be essential events for colorectal cancer development. Recent data seem to indicate that __K‐ras__ and __p53__ mutations rarely co‐exist in the same tumor, indicating that these alterations do not represent a synergistic e