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6-Thioguanosine Diphosphate and Triphosphate Levels in Red Blood Cells and Response to Azathioprine Therapy in Crohn’s Disease

✍ Scribed by NEURATH, M; KIESSLICH, R; TEICHGRABER, U; FISCHER, C; HOFMANN, U; EICHELBAUM, M; GALLE, P; SCHWAB, M


Book ID
123585195
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
330 KB
Volume
3
Category
Article
ISSN
1542-3565

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## Background: To investigate the contribution of multidrug resistance 1 (MDR1) gene pharmacogenetics (G2677T/A and C3435T) to the efficacy of azathioprine in inducing remission in patients with Crohn's disease (CD). ## Methods: A cohort of 327 unrelated Spanish patients with CD recruited from