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6-methyl-1,3,8-trichlorodibenzofuran (MCDF) as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist in C57BL/6 mice

โœ Scribed by R. Bannister; L. Biegel; D. Davis; B. Astroff; S. Safe


Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
596 KB
Volume
54
Category
Article
ISSN
0300-483X

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2,3,7,8-tetrachlorodibenzo-p-dioxin indu
โœ Sparrow, Barney R. ;Thompson, Cynthia S. ;Ryu, Byung-Woo ;Selevonchick, Daniel P ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 765 KB

A dose-dependent reduction of hepatic pyruvate carboxylase levels and activity occurs in C57BL/6J male mice given 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) i.p. in a corn oil carrier. The dose range was from 1 to 75 pg/kg body weight and the analysis was done 8 days postinjection. At the maximum TC