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2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and 2,3,7,8-tetrachlorodibenzofuran (TCDF) in pregnant C57BL/6N mice: distribution to the embryo and excretion

โœ Scribed by H. Weber; L. S. Birnbaum

Publisher
Springer-Verlag
Year
1985
Tongue
English
Weight
410 KB
Volume
57
Category
Article
ISSN
0340-5761

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A dose-dependent reduction of hepatic pyruvate carboxylase levels and activity occurs in C57BL/6J male mice given 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) i.p. in a corn oil carrier. The dose range was from 1 to 75 pg/kg body weight and the analysis was done 8 days postinjection. At the maximum TC