Aromatic hydroxylation is a major metabo
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Erika Pfeiffer; Andreas Hildebrand; Georg Damm; Andreas Rapp; Benedikt Cramer; H
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Article
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2009
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John Wiley and Sons
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English
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## Abstract Zearalenone (ZEN) is a common mycotoxin, for which only reductive metabolites have been identified so far. We now report that ZEN is extensively monohydroxylated by microsomes from human liver __in vitro__. Two of the major oxidative metabolites arise through aromatic hydroxylation and