6-(4-Chlorophenyl)-3-substituted-thieno[3,2- d ]pyrimidin-4(3 H )-one-Based Melanin-Concentrating Hormone Receptor 1 Antagonist
β Scribed by Tavares, Francis X.; Al-Barazanji, Kamal A.; Bishop, Michael J.; Britt, Christy S.; Carlton, David L.; Cooper, Joel P.; Feldman, Paul L.; Garrido, Dulce M.; Goetz, Aaron S.; Grizzle, Mary K.; Hertzog, Donald L.; Ignar, Diane M.; Lang, Daniel G.; McIntyre, Maggie S.; Ott, Ronda J.; Peat, Andrew J.; Zhou, Hui-Qiang
- Book ID
- 120619392
- Publisher
- American Chemical Society
- Year
- 2006
- Tongue
- English
- Weight
- 179 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0022-2623
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract A series of new 2βsubstituted 3β(4βchlorophenyl)β5,8,9βtrimethylthieno[3β²,2β²:β5,6]pyrido[4,3β__d__]pyrimidinβ4(3__H__)βones **8** were synthesized __via__ an azaβ__Wittig__ reaction. Phosphoranylideneamino derivatives **6a** or **6b** reacted with 4βchlorophenyl isocyanate to give carbo
## Abstract magnified image The thienopyridine derivative **2**, obtained from reaction of acetoacetic ester with **1** in the presence of tin tetrachloride, was treated with triphenylphosphine in hexachloroethane and Et~3~N to give iminophosphorane **3**. Iminophosphorane **3** reacted with pheny