๐”– Bobbio Scriptorium
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(5R)-5-hydroxytriptolide (LLDT-8), a novel triptolide analog mediates immunosuppressive effects in vitro and in vivo

โœ Scribed by Ru Zhou; Fan Zhang; Pei-Lan He; Wen-Liang Zhou; Qing-Li Wu; Jian-Yi Xu; Yu Zhou; Wei Tang; Xiao-Yu Li; Yi-Fu Yang; Yuan-Chao Li; Jian-Ping Zuo


Book ID
116575821
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
125 KB
Volume
5
Category
Article
ISSN
1567-5769

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โœ Nakayama, Osamu; Hirosumi, Jiro; Chida, Noboru; Takahashi, Satoru; Sawada, Kozo; ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 524 KB

## BACKGROUND. Steroid 5โฃ-reductase is implicated in the pathogenesis of benign prostatic hyperplasia (BPH). We studied the in vitro and in vivo effects of FR146687, a new inhibitor of 5โฃ-reductase. METHODS. Two isozymes of rat and human 5โฃ-reductases were expressed in 293 cells. In vivo effects o