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590 POSTER Molecular and antiproliferative effects of inhibitors of fatty acid synthase and of ErbB receptors in ovarian cancer cells

โœ Scribed by T.W. Grunt; R. Wagner; W. Shabbir; W. Berger; B. Marian; M. Grusch; C.C. Zielinski; R. Lupu


Book ID
119599746
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
58 KB
Volume
6
Category
Article
ISSN
1359-6349

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Chemical inhibitors of fatty acid synthase (FAS) inhibit growth and induce apoptosis in several cancer cell lines in vitro and in tumor xenografts in vivo. Recently the green tea component epigallocatechin-3-gallate (EGCG) was shown to act as a natural inhibitor of FAS in chicken liver extracts. Her