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58 Genetic control of carcinogen metabolism leading to individual differences in cancer risk

✍ Scribed by Nebert, Daniel W.

Book ID
123467865
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
230 KB
Volume
60
Category
Article
ISSN
0300-9084

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differences exist in the regulation of at least some of the P450s (10). As the molecular mechanisms that underlie induction of human liver P45Os are characterized, it is likely that cell-free assays will be developed to screen drugs for induction properties. These two reports describe recombinant D