𝔖 Bobbio Scriptorium
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5,7-dihydroxy-6,2′,4′,5′-tetramethoxyflavone from the leaves of Chukrasia Tabularis

✍ Scribed by Kozhiparambil K. Purushothaman; Ayyapath Sarada; Ganesan Saraswathi; Joseph D. Connolly


Book ID
107841877
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
236 KB
Volume
16
Category
Article
ISSN
0031-9422

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## Abstract Fusion of an azole moiety at C‐6 and C‐7 of naltrexone (1) is illustrated by the synthesis of the title compound 8. Bromination of 3‐__O__‐methylnaltrexone led to the 1,7α‐dibromo derivative which reacted with thiourea to attach the 2‐aminothiazole ring to C‐6 and C‐7 of naltrexone. Aft