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5,5′-Dihydroxy-3,7,2′,4′-tetramethoxyflavone from Chlorophora excelsa

✍ Scribed by Elfranco Malan; Ewald Swinny; Daneel Ferreira; Alida J. Hall


Book ID
103335439
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
98 KB
Volume
29
Category
Article
ISSN
0031-9422

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## Abstract Fusion of an azole moiety at C‐6 and C‐7 of naltrexone (1) is illustrated by the synthesis of the title compound 8. Bromination of 3‐__O__‐methylnaltrexone led to the 1,7α‐dibromo derivative which reacted with thiourea to attach the 2‐aminothiazole ring to C‐6 and C‐7 of naltrexone. Aft