5,7-Diarylspiro[4,5,6,7-tetrahydrobenzo[d][1,2,3]selena/thiadiazole-6,5′-(hexahydropyrimidine)]-2′,4′,6′-triones/-2′-thioxo-4′,6′-diones from cyclohexanonedicarboxylates: Part V
✍ Scribed by D. Bhaskar Reddy; M. V. Ramana Reddy; V. Padmavathi
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 179 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1042-7163
No coin nor oath required. For personal study only.
✦ Synopsis
The keto and gem-ester functionalities of cyclohexanonedicarboxylates (1) offer a facile route for the synthesis of 5,7-diarylspiro [4,5,6,7-tetrahydrobenzo[d][1,2,3]selena/thiadiazole-6,5Ј-(hexahydropyrimidine)]-2Ј,4Ј,6Ј-triones (6 and 8) and -2Ј-thioxo-4Ј,6Ј-diones (7 and 9). The new compounds were characterized by IR, NMR, and CMR spectral data.
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## Synthesis of 7,12-Dihydro-indo~o[3~[l]benzazepin-6-(~~nes and gll-Dihydr~.thieno-[3'3':~]~zepino[qS-b]indol-5(4H)-one The title compounds 4 and 6 were prepared by Fischer indole synthesis. 4a is substituted in 10-position by reaction with bromine in glacial acetic acid. A fast ring inversion is