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548 Detecting chromosome 9 abnormalities in non-small cell lung cancer (NSCLC) with fluorescent in situ hybridization (FISH)

โœ Scribed by Rayeroux, K.C.; Mead, L.J.; Mitchell, G.; Gillespie, M.T.; Campbell, L.J.; Irving, L.B.

Book ID
123499384
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
289 KB
Volume
18
Category
Article
ISSN
0169-5002

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We examined 82 cases of primary non-small cell lung cancer (NSCLC) for loss of heterozygosity (LOH) at the chromosome 9p21-24 region using 16 microsatellite markers. A total of 52 tumors (63%) displayed LOH, and 25 of these cases displayed LOH for all markers. Two cases had small hemizygous losses c