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Abnormalities in chromosome 17 and p53 in lung carcinoma cells detected by fluorescence in situ hybridization

โœ Scribed by Toshiaki Kawai; Sadayuki Hiroi; Kuniaki Nakanishi; Yutaka Sakurai; Chikao Torikata

Book ID
115175324
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
331 KB
Volume
54
Category
Article
ISSN
1320-5463

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## Background: A fluorescence in situ hybridization (fish) technique using specific dna probes allows for the detection of chromosomal aberrations and gene deletions and gains, even in interphase nuclei in human solid tumors. a high frequency of aberrations of chromosome 17 and mutation of the p53