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545 Aberrant Vimentin Methylation in Esophageal Brushings: A Biomarker for Detecting Barrett's Esophagus and Esophageal Adenocarcinoma

✍ Scribed by Chak, Amitabh; Moinova, Helen; Lutterbaugh, James; Chandar, Apoorva; Willis, Joseph; Markowitz, Sanford


Book ID
122311831
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
222 KB
Volume
146
Category
Article
ISSN
0016-5085

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## Abstract Hypermethylation of secreted frizzled‐related proteins (__SFRP__) genes frequently occurs with several cancers but has not been studied in esophageal adenocarcinoma or its precursorβ€”Barrett's esophagus. To explore the role of __SFRP__ methylation in the neoplastic progression of Barrett