537 Analysis of the Codon 72 Polymorphism of P53 Gene in Patients With Multinodular Goiter to Develop Thyroid Cancer
β Scribed by B. Bayram; R. Sonmez; S. Bozari; H. Onlu
- Book ID
- 117663032
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 52 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0959-8049
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This study was conducted to evaluate the frequency and prognostic impact of TP53 alterations stratified for the TP53 codon 72 polymorphism (c.215G4C, p.Arg72Pro) in a cohort of 109 patients with advanced ovarian carcinomas. TP53 sequence variants were observed in 80 of the 109 (73.4%) tumors and wer
The original article to which this Erratum refers was published in Human Mutation 24: 21-34 (2004). Using a newly developed method-Arrayed Primer Extension (APEX) and direct sequencing of exon 10 and 11 to reanalyze for TP53 sequence alterations-13 new mutations were identified. In addition, a few