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532 BOTH IMPAIRED SPERMATOGENESIS AND TESTICULAR CANCER IS ASSOCIATED WITH ABERRANT EXPRESSION OF DNA-METHYLTRANSFERASE-1 (DNMT1)

✍ Scribed by K. Steger; O. Omisanjo; L. Heukamp; K. Biermann; W. Weidner


Book ID
119617862
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
316 KB
Volume
6
Category
Article
ISSN
1569-9056

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## Abstract Alteration of DNA methylation is one of the most consistent epigenetic changes in human cancers. DNA methyltransferase (DNMT) 1 is a major enzyme involved in establishing genomic methylation patterns. Most of the studies concerning DNMT1 expression in human cancers have been performed o