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5-Hydroxytryptamine Evokes Endothelial Nitric Oxide Synthase Activation in Bovine Aortic Endothelial Cell Cultures

✍ Scribed by J. Eric Mcduffie; Sonya D. Coaxum; Mohammed A. Maleque

Book ID: 118677601
Publisher: Royal Society of Medicine Press
Year: 1999
Tongue: English
Weight: 388 KB
Volume: 221
Category: Article
ISSN: 0037-9727
DOI: 10.1046/j.1525-1373.1999.d01-97.x

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## Abstract Cultured cells derived from the cerebromicrovasculature can be shown to contain the enzyme nitric oxide synthase (NOS) by NADPH diaphorase staining. Nos is located largely as a distinct crescent adjacent to the nuclear membrane. NOS in these cells appears to be associated with the micro