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5-(Hydroxymethyl)oxazoles: Versatile Scaffolds for Combinatorial Solid-Phase Synthesis of 5-Substituted Oxazoles

โœ Scribed by Grabowska, Urszula; Rizzo, Adriana; Farnell, Kevin; Quibell, Martin


Book ID
127075693
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
532 KB
Volume
2
Category
Article
ISSN
1520-4766

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โœ Jennifer D Kreisberg; Philip Magnus; Shirin Shinde ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 230 KB

Treatment of N-acylamino-2-thiophenyl derivatives with N-chlorosuccinimide (2.0 equiv.) followed by SnCl 4 (0.1-1.0 equiv.) provides a direct synthesis of 5-thiophenyloxazoles.