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5-hydroxydecanoate inhibits ATP-sensitive K+ channel currents in guinea-pig single ventricular myocytes

โœ Scribed by Tatsuto Notsu; Kiyokazu Ohhashi; Isao Tanaka; Hiroshi Ishikawa; Takeshi Niho; Katsuhiko Fukutake; Masahiro Mizota

Book ID
115887340
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
584 KB
Volume
220
Category
Article
ISSN
0014-2999

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Patch-clamp techniques were used to study the effects of three carbonyl compounds, 3,4-dihydroxybenzaldehyde, 2,3-dihydroxybenzaldehyde, and 2,4-dihydroxyacetophenone, on the adenosine-5'-triphosphate(ATP)-sensitive K+ channel current (IK.ATP) in guinea-pig ventricular myocytes. 3,4-Dihydroxybenzald