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Proteolytic digestion with trypsin prevents ‘run-down’ of ATP-sensitive K+ channel of guinea-pig ventricular myocytes

✍ Scribed by Tetsushi Furukawa; Fan Zheng; Tohru Sawanobori; Masayasu Hiraoka


Book ID
115983882
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
107 KB
Volume
24
Category
Article
ISSN
0022-2828

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Pinacidil activates the ATP-sensitive K+
✍ Zheng Fan; Keiko Nakayama; Masayasu Hiraoka 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 966 KB

Patch-clamp techniques were used to study the effects of pinacidil on the adenosine-5'-triphosphate (ATP)sensitive K + channel current in guinea-pig ventricular myocytes. In inside-out patches, the ATP-sensitive K + channel current could be recorded at an internal ATP concentration of 0.5 mM or tess