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5-HT2A and α1b-adrenergic receptors entirely mediate dopamine release, locomotor response and behavioural sensitization to opiates and psychostimulants

✍ Scribed by Agnès Auclair; Candice Drouin; Susanna Cotecchia; Jacques Glowinski; Jean-Pol Tassin

Book ID
110100352
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
354 KB
Volume
20
Category
Article
ISSN
0953-816X

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Herein, we evaluate the interaction of the ␣ 2 -AR antagonist, yohimbine, as compared to fluparoxan, at multiple monoaminergic receptors and examine their roles in the modulation of adrenergic, dopaminergic and serotonergic transmission in freelymoving rats. Yohimbine displays marked affinity at hum