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P-4-12 In vitro and ex vivo patterns of occupation of 5-HT2A and α1-adrenergic as compared to dopamine D2 receptors by novel antipsychotics

✍ Scribed by V. Audinot; H. Canton; A. Newman-Tancredi; V. Jacques; L. Verrièle; M.J. Millan


Book ID
119176238
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
133 KB
Volume
5
Category
Article
ISSN
0924-977X

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Herein, we evaluate the interaction of the ␣ 2 -AR antagonist, yohimbine, as compared to fluparoxan, at multiple monoaminergic receptors and examine their roles in the modulation of adrenergic, dopaminergic and serotonergic transmission in freelymoving rats. Yohimbine displays marked affinity at hum