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5-HT1A receptor agonists reduce ethanol-induced locomotor activity in mice

✍ Scribed by Blomqvist, Ola; Söderpalm, Bo; Engel, Jörgen A.

Book ID
121999761
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
477 KB
Volume
11
Category
Article
ISSN
0741-8329

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The eects of 5-HT1B/D receptor agonists anpirtoline, S-CM-GTNH2 and CP93129 were examined in locomotor activity tests in mice. Anpirtoline and S-CM-GTNH2 both signi®cantly increased locomotor activity (ambulation) (minimum aective doses; 3 and 30 mg/kg respectively). CP 93129 injected subcutaneously