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5-Fluorouracil incorporated into the tissue RNA of human and rat bladder carcinoma after administration of 1-(2-tetrahydrofuryl)-5-fluorouracil combined with uracil

✍ Scribed by Shigehiro Tsujimoto; Kiyohide Fujimoto; Eijiro Okajima; Seiichiro Ozono; Eigoro Okajima; Yoshihiko Hirao


Publisher
Springer
Year
2008
Tongue
English
Weight
220 KB
Volume
13
Category
Article
ISSN
1341-9625

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Relation between the incorporation of 5-
✍ Gunnel Roos; Dr. Unne Stenram πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 388 KB

The cytotoxicity of 5-FUra has been related to its incorporation into RNA. In a model of secondary liver cancer in the rat, the incorporation of 5-FUra into the acid-soluble fraction, RNA and DNA of several normal tissues and an adenocarcinoma of the colon transplanted to the liver was determined. A